XTANDI (Enzalutamide) is very much like Zytiga…..a previously approved medications for advanced prostate cancer. The medication is a pill that maximally suppressed all testosterone in the body and thereby deprives the prostate cancer cells of any testosterone, a hormone which assists in prostate tissue growth. The advantage of XTANDI is that is does not require prednisone, like Zytiga dose, and this may be a benefit.
There is hope that XTANDI and ZYTIGA will be used prior to trying IV chemotherapy, but they have not yet been approved for these purposes, so they remain a ‘last line’ therapy. That, and the cost (approx $7,000 per month) are among the limiters for this new medication, but it is great to have more weapons at our disposal.